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NEWS


  • Full partnership in the Interreg IDEA NWE Project on the culture of microalgae

  • News 1

  • The Interreg IDEA NWE (Implementation and development of economic viable algae-based value chains in NWE) has been approved by Europe and has officially started since September 2017 with a total budget of 5 M€. The project aims to construct a microalgae valorisation chain based on the existing investment in green houses in Northern Europe that are at present surplus to agricultural requirement. This project, that will run until the end of 2020, includes 10 partners whom represent the entire value chain from green house owners, to microalgae growers, to extraction centres and to feed manufacturers. The Chair of Biotechnology of CentraleSupélec (Chair of CS) as well as the other technical partners of the project will aim to overcome the main challenges that the northern European climate presents to microalgae growers, namely those of short winter photoperiods and low ambient temperatures. The Chair of CS in involved in optimising the growth conditions of selected strains for either direct incorporation into feed or extraction of oils, pigments and proteins that may be subsequently used for high value applications. Additionally, the Chair of CS will develop quality markers that could be used to monitor potential degradation of the high value compounds during algae harvesting and transport and then during the extraction of these compounds.
  • Installing of downsized bioreactors for process upscaling

  • News 1

  • The Chair of Biotechnology installed and tested 8 parallel downsized bioreactors.

    These identical bioreactors allow reproduction of industrial conditions at small scale and in particular the variation of pressure over time. The development of pressurized mini-bioreactors will scale down microbial cultures under conditions similar to industrial scale. Thus they could lead to the optimization of scale-up procedures, especially when combined with hydrodynamic models.

    With these mini-bioreactors, extensive data under different culture conditions can be obtained. In addition, those data will be used to develop and tune mathematical models relating changes in pressure and microbial growth performance. Such robust models are likely to be used for upscaling bioreactors up to the industrial scale.
  • The Chair of Biotechnology at the European Researchers’ Night

  • News 1

  • On Friday 28th September, a Researchers' Night event has been organized by Accustica, the University of Reims Champagne-Ardenne, and the Planetarium of Reims. During a Speed Searching, Wuyang Zhong and Hassan Khalil — two PhD students at the Chair of Biotechnology of CentraleSupélec — presented their research about a New sugar purification process and the Solid-state fermentation, respectively.

WHO ARE WE?

The Chair of Biotechnology of CentraleSupélec, launched in 2010 and located in the Centre Européen de Biotechnologie et de Bioéconomie (CEBB), has three areas of expertise:

  • Characterization & conversion of lignocellulosics,
  • Biotransformation,
  • Downstream processing.

Backed by the Process Engineering and Materials Laboratory, this chair is a strong link between its head institution – CentraleSupélec – and economic and academic actors; most of the R&D activities are led in regional, national and international collaborative projects. With its training of high-level general engineers, CentraleSupélec has a strong expertise in modeling applied to (bio)process and (bio)materials. Thus, in addition to the experimental approach, the three areas of expertise of the Chair significantly rely on a set of core skills in Modeling, Simulation & Visualization, more particularly oriented towards the modeling of life mechanisms and the up-scaling of processes for the industry.

Our brochure in English.

EXPERTISE AREAS

  • Characterization and conversion of lignocellulosics track

  • Axe 1

  • Our advanced characterization techniques are applied to the study of the physico-mechanical properties of lignocellulosic materials (3D-BioMat project). They are involved in both the optimization of pretreatment processes for energy and the design of innovative bio-based materials.
  • Biotransformation track

  • Axe 2

  • CentraleSupélec’s long standing expertise in process engineering is applied to biotransformation with the aim of producing high-value compounds, processing industrial effluents or system optimization for growth control and new (photo)bioreactor design.
  • Separation techniques track

  • Axe 3

  • Our vocation is to develop effective, sober and sustainable separation processes to extract and purify biosourced molecules. In addition, we offer solutions for upgrading industrial effluents and co-products (lignocellulose, pentoses, biogas, etc.).

OUR FLAGSHIP EQUIPMENTS


Equipement 1

Chromatography is the core of our analytical platform. UHPLC, HPLC, IC and GC technologies, coupled with RI, FLD, UV, MS and Orbitrap detectors, and supplemented by ICP-OES, AAS and CHNS/O analyzers allow to identify and quantify a wide range of organic and inorganic compounds. In addition, cell counter and RT-qPCR are used for monitoring cell cultures.

  • Our key equipments:
  • HPLC
  • Gas chromatography
  • qPCR
  • Cell counter

Analytical platform

Bleeding edge equipments to better analyze and valorize bioressources

Chromatography is the core of our analytical platform. UHPLC, HPLC, IC and GC technologies, coupled with RI, FLD, UV, MS and Orbitrap detectors, and supplemented by ICP-OES, AAS and CHNS/O analyzers allow to identify and quantify a wide range of organic and inorganic compounds. In addition, cell counter and RT-qPCR are used for monitoring cell cultures.

Equipement 2

The upscaling of separation processes is based on a fleet of laboratory pilots, located in a dedicated hall: ultra-, nano-filtration and reverse osmosis, conventional and bipolar electrodialysis, preparative chromatography, continuous ion exchange and gas-liquid absorption with membrane contactors.

  • Our key equipments:
  • Ultra- and nano-filtrations
  • Reverse osmosis and electrodialysis
  • Preparative chromatography
  • Membrane contactors

Laboratory pilots fleet

A link to secure the transfer of innovation to industry

The upscaling of separation processes is based on a fleet of laboratory pilots, located in a dedicated hall: ultra-, nano-filtration and reverse osmosis, conventional and bipolar electrodialysis, preparative chromatography, continuous ion exchange and gas-liquid absorption with membrane contactors.


Equipement 3

The Chair of Biotechnology possesses of a considerable range of equipment adapted for the culture, analysis and treatment of microscopic cell (plant, bacteria, yeasts and fungi as well as microalgae). The cultures can be grown at different scales: petri-dish, shake-flask, 2-20 L (photo)bioreactor. In addition to the 20 L pilot-scale bioreactor, a fully automated 30 L raceway pond allows the initial stages of scale-up of photosynthetic cultures.

  • Our key equipments:
  • Bioreactors
  • Photobioreactors
  • Raceway ponds
  • Incubators

Growth systems

The biological factory aiming to produce high added-value molecules

The Chair of Biotechnology possesses of a considerable range of equipment adapted for the culture, analysis and treatment of microscopic cell (plant, bacteria, yeasts and fungi as well as microalgae). The cultures can be grown at different scales: petri-dish, shake-flask, 2-20 L (photo)bioreactor. In addition to the 20 L pilot-scale bioreactor, a fully automated 30 L raceway pond allows the initial stages of scale-up of photosynthetic cultures.

Equipement 4

Diagnosis, quantitative analysis and modeling on real morphology with temporal evolution rely on the imagery platform. Our X-ray nano-tomograph, microscopes (confocal, Raman ESEM) and structured illumination macroscope allow the acquisition of high-resolution images in 2D, 3D and 4D that are compatible with digital post-processing.

  • Our key equipments:
  • Xray nano-tomograph
  • Raman microscops
  • Confocal microscope
  • SEM

Imagery platform

Observe what is infinity small to optimize industrial processes

Diagnosis, quantitative analysis and modeling on real morphology with temporal evolution rely on the imagery platform. Our X-ray nano-tomograph, microscopes (confocal, Raman ESEM) and structured illumination macroscope allow the acquisition of high-resolution images in 2D, 3D and 4D that are compatible with digital post-processing.

Contact

Address

Centre Européen de Biotechnologie et de Bioéconomie
3, rue des Rouges Terres
51110 Pomacle, France

GPS : 49.346017, 4.156493

E-mail

chaire-biotechnologie@centralesupelec.fr

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